M. lignano Ageing Data Search

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Found 124 results for path Up-Up-Up. Showing entries 1-20.

Graph	Cluster	Transcripts	Mean logCPM	logFC M26/M2	FDR M26/M2	Classification	Human genes	C.elegans genes	Annotation
1.	MligTC455_24833	Mlig455_044748	9.77	1.373	0.000	Up-Up-Up GM2A	GM2 ganglioside activator		Mlig455_044748 {REF} {Length: 1032} {Pfam: ML domain [PF02221.17, score=45.6]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=62.0, Expect=3e-11]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=64.3, Expect=3e-12]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [RH, Score=89.4, Expect=4e-22]} {RNA1509_1066, RNA1509_8277} {RNA1310_42438, RNA1509_1066} {RNA1509_1066, RNA815_22343} {SMEDTYPE: Xins [raj_facs_types]}
2.	MligTC455_31501	Mlig455_056609	9.7	0.808	0.000	Up-Up-Up			Mlig455_056609 {REF} {Length: 1337} {RNA1509_38749, RNA1509_41088} {RNA1310_32308, RNA1509_41088} {RNA1509_41088, RNA815_5913.2}
3.	MligTC455_22631	Mlig455_007773	9.66	0.952	0.000	Up-Up-Up TMPRSS9	transmembrane serine protease 9	try-1	Mlig455_007773 {REF} {Length: 1686} {Pfam: Trypsin [PF00089.28, score=249.9]; CUB domain [PF00431.22, score=105.1]; Low-density lipoprotein receptor domain class A [PF00057.20, score=46.9]; Trypsin-like peptidase domain [PF13365.8, score=33.1]; Domain of unknown function (DUF1986) [PF09342.13, score=27.4]} {Human: ENSG00000178297, TMPRSS9, transmembrane serine protease 9, [RH, Score=218, Expect=9e-63]; ENSG00000122194, PLG, plasminogen, [RH, Score=211, Expect=1e-60]; ENSG00000149418, ST14, suppression of tumorigenicity 14, [RH, Score=208, Expect=3e-59]} {Mouse: ENSMUSG00000059406, Tmprss9, transmembrane protease, serine 9, [RH, Score=217, Expect=1e-61]; ENSMUSG00000031995, St14, suppression of tumorigenicity 14 (colon carcinoma), [RH, Score=211, Expect=2e-60]; ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [RH, Score=209, Expect=1e-59]} {Dmel: FBgn0033192, Corin, [RH, Score=184, Expect=1e-50]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [RH, Score=165, Expect=9e-48]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=175, Expect=1e-47]} {RNA1509_10189, RNA1509_254, RNA1509_423, RNA1509_8940} {RNA1310_22739.1, RNA1509_10189, RNA1509_254, RNA1509_423, RNA1509_8940} {RNA1509_10189, RNA1509_254, RNA1509_423, RNA1509_8940, RNA815_6357.1} {SMEDTYPE: Gamma neoblasts [dd_Smed_v6_790_0_1, protease, serine, 12 (neurotrypsin, motopsin) (PRSS12)]} {SMEDTYPE: Xins [raj_facs_types]} {SMEDTYPE: Asexual_biased [CUFF.89211.1]}
4.	MligTC455_40106	Mlig455_062776	9.06	1.171	0.000	Up-Up-Up			Mlig455_062776 {REF} {Length: 2372} {Pfam: D-lyxose isomerase [PF07385.14, score=40.7]; Glutathione-dependent formaldehyde-activating enzyme [PF04828.16, score=22.1]} {RNA1509_347} {RNA1310_44581.1} {RNA815_12017.1}
5.	MligTC455_30405	Mlig455_010049, Mlig455_010004	8.69	1.566	0.000	Up-Up-Up CPA2	carboxypeptidase A2	T06A4.1	Mlig455_010049 {REF} {Length: 1546} {Pfam: Zinc carboxypeptidase [PF00246.26, score=261.1]} {Human: ENSG00000158516, CPA2, carboxypeptidase A2, [Score=220, Expect=2e-66]} {Mouse: ENSMUSG00000071553, Cpa2, carboxypeptidase A2, pancreatic, [Score=227, Expect=3e-69]} {Dmel: FBgn0032144, CG17633, [RH, Score=242, Expect=3e-75]} {Celegans: WBGene00020281, T06A4.1, [Score=215, Expect=2e-63]} {Smed: dd_Smed_v6_2541_0_1, dd_Smed_v6_2541_0_1, [RH, Score=257, Expect=3e-81]} {RNA1509_334} {RNA1310_22015} {RNA815_8491} Mlig455_010004 {REF} {Length: 1499} {Pfam: Zinc carboxypeptidase [PF00246.26, score=261.4]} {Human: ENSG00000158516, CPA2, carboxypeptidase A2, [Score=221, Expect=5e-67]} {Mouse: ENSMUSG00000071553, Cpa2, carboxypeptidase A2, pancreatic, [Score=228, Expect=6e-70]} {Dmel: FBgn0032144, CG17633, [RH, Score=240, Expect=1e-74]} {Celegans: WBGene00020281, T06A4.1, [Score=214, Expect=3e-63]} {Smed: dd_Smed_v6_2541_0_1, dd_Smed_v6_2541_0_1, [RH, Score=257, Expect=2e-81]} {RNA1509_334, RNA1509_3364} {RNA1310_22015, RNA1509_334, RNA1509_3364} {RNA1509_334, RNA1509_3364, RNA815_8491}
6.	MligTC455_22522	Mlig455_012846	8.46	1.211	0.000	Up-Up-Up SERP2	stress associated endoplasmic reticulum protein family member 2	T09A12.5	Mlig455_012846 {REF} {Length: 1870} {TRANSSPLICED} {Pfam: Haemolymph juvenile hormone binding protein (JHBP) [PF06585.13, score=156.3]; Group 7 allergen [PF16984.7, score=100.5]; Ribosome associated membrane protein RAMP4 [PF06624.14, score=75.9]} {Human: ENSG00000151778, SERP2, stress associated endoplasmic reticulum protein family member 2, [Score=82.4, Expect=6e-19]} {Mouse: ENSMUSG00000052584, Serp2, stress-associated endoplasmic reticulum protein family member 2, [Score=82.4, Expect=4e-19]} {Dmel: FBgn0038395, CG10407, [RH, Score=87.0, Expect=6e-19]} {Celegans: WBGene00020374, T09A12.5, [Score=77.0, Expect=2e-17]} {Smed: dd_Smed_v6_304_0_1, dd_Smed_v6_304_0_1, [Score=93.6, Expect=2e-23]} {RNA1509_13349, RNA1509_47821} {RNA1310_21535.1, RNA1509_47821} {RNA1509_47821, RNA815_6279.1} {SMEDTYPE: X2 [raj_facs_types]}
7.	MligTC455_50368	Mlig455_009542	8.19	1.173	0.000	Up-Up-Up			Mlig455_009542 {REF} {Length: 524} {RNA1509_1137, RNA1509_491, RNA1509_924} {RNA1310_65230.2, RNA1509_1137, RNA1509_491, RNA1509_924} {RNA1509_1137, RNA1509_491, RNA1509_924, RNA815_32028.1}
8.	MligTC455_22632	Mlig455_056621	8.14	1.479	0.000	Up-Up-Up TMPRSS9	transmembrane serine protease 9	try-1	Mlig455_056621 {REF} {Length: 1688} {Pfam: Trypsin [PF00089.28, score=252.4]; CUB domain [PF00431.22, score=105.1]; Low-density lipoprotein receptor domain class A [PF00057.20, score=46.9]; Trypsin-like peptidase domain [PF13365.8, score=33.6]; Domain of unknown function (DUF1986) [PF09342.13, score=28.8]} {Human: ENSG00000178297, TMPRSS9, transmembrane serine protease 9, [RH, Score=218, Expect=1e-62]; ENSG00000122194, PLG, plasminogen, [RH, Score=216, Expect=5e-62]; ENSG00000187950, OVCH1, ovochymase 1, [RH, Score=210, Expect=3e-59]; ENSG00000149418, ST14, suppression of tumorigenicity 14, [RH, Score=209, Expect=1e-59]} {Mouse: ENSMUSG00000059406, Tmprss9, transmembrane protease, serine 9, [RH, Score=216, Expect=1e-61]; ENSMUSG00000031995, St14, suppression of tumorigenicity 14 (colon carcinoma), [RH, Score=213, Expect=7e-61]} {Dmel: FBgn0033192, Corin, [RH, Score=182, Expect=5e-50]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [RH, Score=166, Expect=7e-48]} {Smed: dd_Smed_v6_2492_0_1, dd_Smed_v6_2492_0_1, [Score=167, Expect=5e-48]} {RNA1509_254} {RNA1310_22739.1} {RNA815_6357.1} {SMEDTYPE: Neural (non-ciliated) [dd_Smed_v6_2492_0_1, kallikrein B, plasma (Fletcher factor) 1 (KLKB1)]} {SMEDTYPE: Xins [raj_facs_types]} {SMEDTYPE: Asexual_biased [CUFF.619020.0]}
9.	MligTC455_27241	Mlig455_053246	8.13	2.221	0.000	Up-Up-Up GM2A	GM2 ganglioside activator		Mlig455_053246 {REF} {Length: 888} {Pfam: ML domain [PF02221.17, score=40.0]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=51.6, Expect=8e-08]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=50.8, Expect=1e-07]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [Score=56.2, Expect=4e-10]} {RNA1509_180, RNA1509_30371, RNA1509_960} {RNA1310_28835.1, RNA1509_180, RNA1509_30371, RNA1509_960} {RNA1509_180, RNA1509_30371, RNA1509_960, RNA815_6681.1} {SMEDTYPE: Xins [raj_facs_types]}
10.	MligTC455_27180	Mlig455_061198	8.11	-0.424	0.113	Up-Up-Up			Mlig455_061198 {REF} {Length: 1211} {NoTransDecoderORF} {RNA1509_3, RNA1509_60} {RNA1310_851.1, RNA1509_60} {RNA1509_60, RNA815_80.1}
11.	MligTC455_28965	Mlig455_057874	7.74	1.849	0.000	Up-Up-Up			Mlig455_057874 {REF} {Length: 2629} {Pfam: Haemolymph juvenile hormone binding protein (JHBP) [PF06585.13, score=162.8]; Group 7 allergen [PF16984.7, score=94.8]} {Dmel: FBgn0038395, CG10407, [Score=80.1, Expect=1e-16]} {Smed: dd_Smed_v6_888_0_1, dd_Smed_v6_888_0_1, [RH, Score=100, Expect=5e-24]} {RNA1509_247} {RNA1310_15275, RNA1509_247} {RNA1509_247, RNA815_5759} {SMEDTYPE: Gut [dd_Smed_v6_888_0_1, NA]} {SMEDTYPE: Xins [raj_facs_types]} {SMEDTYPE: Sexual_biased [CUFF.354339.1]}
12.	MligTC455_48308	Mlig455_043565	7.61	0.785	0.000	Up-Up-Up			Mlig455_043565 {REF} {Length: 1273} {TRANSSPLICED} {Pfam: Sep15/SelM redox domain [PF08806.13, score=20.1]} {RNA1509_934} {RNA1310_24649.1, RNA1509_934} {RNA1509_934, RNA815_12206}
13.	MligTC455_46093	Mlig455_045924	7.18	1.591	0.000	Up-Up-Up			Mlig455_045924 {REF} {Length: 1551} {Smed: dd_Smed_v6_279_0_1, dd_Smed_v6_279_0_1, [Score=162, Expect=6e-45]} {RNA1509_1008, RNA1509_24685, RNA1509_29824, RNA1509_7946} {RNA1310_17956, RNA1509_1008, RNA1509_24685, RNA1509_29824, RNA1509_7946} {RNA1509_1008, RNA1509_24685, RNA1509_29824, RNA1509_7946, RNA815_7079.1} {SMEDTYPE: Xins [raj_facs_types]}
14.	MligTC455_37186	Mlig455_049358	7.1	1.615	0.000	Up-Up-Up			Mlig455_049358 {REF} {Length: 1834} {Pfam: QacR-like protein, C-terminal region [PF08360.13, score=18.9]} {RNA1509_252} {RNA1310_4046.2} {RNA815_6338.1}
15.	MligTC455_28964	Mlig455_021219, Mlig455_021173	7.04	2.165	0.000	Up-Up-Up			Mlig455_021219 {REF} {Length: 1585} {Pfam: Haemolymph juvenile hormone binding protein (JHBP) [PF06585.13, score=162.4]; Group 7 allergen [PF16984.7, score=95.4]} {Dmel: FBgn0037288, CG14661, [RH, Score=76.3, Expect=2e-15]} {Smed: dd_Smed_v6_888_0_1, dd_Smed_v6_888_0_1, [RH, Score=100, Expect=6e-24]} {RNA1509_1643, RNA1509_247} {RNA1310_15275, RNA1509_1643} {RNA1509_1643, RNA815_5759} {SMEDTYPE: Gut [dd_Smed_v6_888_0_1, NA]} {SMEDTYPE: Xins [raj_facs_types]} {SMEDTYPE: Sexual_biased [CUFF.354339.1]} Mlig455_021173 {REF} {Length: 1585} {Pfam: Haemolymph juvenile hormone binding protein (JHBP) [PF06585.13, score=162.4]; Group 7 allergen [PF16984.7, score=95.4]} {Dmel: FBgn0037288, CG14661, [RH, Score=76.3, Expect=2e-15]} {Smed: dd_Smed_v6_888_0_1, dd_Smed_v6_888_0_1, [RH, Score=100, Expect=6e-24]} {RNA1509_247} {RNA1310_15275} {RNA815_5759} {SMEDTYPE: Gut [dd_Smed_v6_888_0_1, NA]} {SMEDTYPE: Xins [raj_facs_types]} {SMEDTYPE: Sexual_biased [CUFF.354339.1]}
16.	MligTC455_47523	Mlig455_066733	7.01	0.639	0.000	Up-Up-Up PRDX6	peroxiredoxin 6	prdx-6	Mlig455_066733 {REF} {Length: 1378} {Pfam: AhpC/TSA family [PF00578.23, score=93.9]; Redoxin [PF08534.12, score=43.8]; C-terminal domain of 1-Cys peroxiredoxin [PF10417.11, score=35.1]} {Human: ENSG00000117592, PRDX6, peroxiredoxin 6, [RH, Score=270, Expect=5e-92]} {Mouse: ENSMUSG00000026701, Prdx6, peroxiredoxin 6, [RH, Score=262, Expect=5e-89]; ENSMUSG00000050114, Prdx6b, peroxiredoxin 6B, [RH, Score=251, Expect=2e-84]} {Dmel: FBgn0031479, Prx6005, Peroxiredoxin 6005, [RH, Score=253, Expect=1e-85]} {Celegans: WBGene00021401, prdx-6, PeRoxireDoXin, [RH, Score=222, Expect=1e-73]} {Smed: dd_Smed_v6_3299_0_1, dd_Smed_v6_3299_0_1, [RH, Score=226, Expect=2e-75]} {RNA1509_12645, RNA1509_5350, RNA1509_932} {RNA1310_32794.1, RNA1509_12645, RNA1509_5350, RNA1509_932} {RNA1509_12645, RNA1509_5350, RNA1509_932, RNA815_15092} {SMEDTYPE: X2 [raj_facs_types]} {SMEDTYPE: Sexual_biased [CUFF.78918.0]}
17.	MligTC455_44136	Mlig455_024714, Mlig455_024689	6.96	0.859	0.000	Up-Up-Up FADS2	fatty acid desaturase 2	fat-3	Mlig455_024714 {REF} {Length: 5232} {TRANSSPLICED} {Pfam: Fatty acid desaturase [PF00487.26, score=117.3]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=75.0]} {Human: ENSG00000134824, FADS2, fatty acid desaturase 2, [RH, Score=430, Expect=3e-148]; ENSG00000149485, FADS1, fatty acid desaturase 1, [RH, Score=427, Expect=2e-146]} {Mouse: ENSMUSG00000024665, Fads2, fatty acid desaturase 2, [RH, Score=447, Expect=3e-155]} {Dmel: FBgn0029854, CG3566, [Score=56.2, Expect=7e-10]} {Celegans: WBGene00001395, fat-3, Delta(6)-fatty-acid desaturase fat-3, [Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [Score=328, Expect=6e-109]} {RNA1509_9754} {RNA1310_4526} {RNA815_4497} {SMEDTYPE: X2 [raj_facs_types]} {SMEDTYPE: repression [28]} Mlig455_024689 {REF} {Length: 3861} {TRANSSPLICED} {Pfam: Fatty acid desaturase [PF00487.26, score=116.9]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=75.0]} {Human: ENSG00000134824, FADS2, fatty acid desaturase 2, [RH, Score=429, Expect=6e-148]; ENSG00000149485, FADS1, fatty acid desaturase 1, [RH, Score=426, Expect=8e-146]} {Mouse: ENSMUSG00000024665, Fads2, fatty acid desaturase 2, [RH, Score=446, Expect=7e-155]} {Dmel: FBgn0029854, CG3566, [Score=56.2, Expect=7e-10]} {Celegans: WBGene00001395, fat-3, Delta(6)-fatty-acid desaturase fat-3, [Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [Score=328, Expect=3e-109]} {RNA1509_1792, RNA1509_9754} {RNA1310_4526, RNA1509_1792, RNA1509_9754} {RNA1509_1792, RNA1509_9754, RNA815_4497} {SMEDTYPE: X2 [raj_facs_types]} {SMEDTYPE: repression [28]}
18.	MligTC455_53287	Mlig455_044750, Mlig455_026458, Mlig455_026427	6.94	2.125	0.000	Up-Up-Up			Mlig455_044750 {REF} {Length: 1007} {RNA1509_1133} {RNA1310_35864} {RNA815_17135} Mlig455_026458 {REF} {Length: 978} {RNA1509_1133, RNA1509_15587} {RNA1310_35864, RNA1509_1133, RNA1509_15587} {RNA1509_1133, RNA1509_15587, RNA815_17135} Mlig455_026427 {REF} {Length: 1166} {RNA1509_15587} {RNA1310_35864} {RNA815_17135}
19.	MligTC455_52027	Mlig455_038451	6.88	2.259	0.000	Up-Up-Up NPC2	NPC intracellular cholesterol transporter 2		Mlig455_038451 {REF} {Length: 1128} {Pfam: ML domain [PF02221.17, score=98.8]} {Human: ENSG00000119655, NPC2, NPC intracellular cholesterol transporter 2, [RH, Score=127, Expect=1e-37]} {Mouse: ENSMUSG00000021242, Npc2, NPC intracellular cholesterol transporter 2, [Score=116, Expect=7e-34]} {Dmel: FBgn0031381, Npc2a, Niemann-Pick type C-2a, [RH, Score=129, Expect=8e-39]} {Smed: dd_Smed_v6_602_0_1, dd_Smed_v6_602_0_1, [RH, Score=129, Expect=3e-39]} {RNA1509_19406, RNA1509_27769, RNA1509_2995, RNA1509_4004, RNA1509_42381, RNA1509_45875, RNA1509_56738} {RNA1310_12229, RNA1509_19406, RNA1509_27769, RNA1509_2995, RNA1509_4004, RNA1509_42381, RNA1509_45875, RNA1509_56738} {RNA1509_19406, RNA1509_27769, RNA1509_2995, RNA1509_4004, RNA1509_42381, RNA1509_45875, RNA1509_56738, RNA815_4030} {SMEDTYPE: Gut [dd_Smed_v6_602_0_1, Niemann-Pick disease, type C2 (NPC2)]} {SMEDTYPE: Xins [raj_facs_types]}
20.	MligTC455_40105	Mlig455_003114	6.87	1.346	0.000	Up-Up-Up			Mlig455_003114 {REF} {Length: 1338} {Pfam: D-lyxose isomerase [PF07385.14, score=33.9]} {RNA1509_20545, RNA1509_54742} {RNA1310_52351, RNA1509_54742} {RNA1509_54742, RNA815_12017.1}

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